HitPredict

Interactor 1: EPHB1 (P54762)
Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)
Gene: EPHB1

Interactor 2: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 984 Hs			1 2221
+	Hs
		665598 EPHB2_HUMAN (19-981): 0: 1198: 73.76		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047091 EPHA7_HUMAN (1-981): 0: 1151: 56.96		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872644 EPHA4_HUMAN (13-983): 0: 1150: 59.10		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872439 EPHA5_HUMAN (1-981): 0: 1143: 55.78		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665395 EPHA3_HUMAN (14-981): 0: 1131: 55.67		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047303 EPHA6_HUMAN (1-982): 0: 1098: 52.04		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665475 EPHA8_HUMAN (19-981): 0: 1061: 51.78		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		412186 FYN_HUMAN (613-879): 2.52e-64: 228: 42.54		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872476 EPHA5_HUMAN (1-981): 0: 1143: 55.78		SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45
+	Hs
		242616 FYN_HUMAN (613-879): 2.52e-64: 228: 42.54		CAC1F_HUMAN (1860-2191): 6.18e-21: 103: 24.14