HitPredict

Interactor 1: C9J2Y9 (C9J2Y9)
DNA-directed RNA polymerase subunit beta (EC 2.7.7.6)
Gene: POLR2B

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RNA_pol_Rpb2_7~S1, RNA_pol_Rpb2_7~SHS2_Rpb7-N
Common GO terms	GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1167 Hs			1 172
+	Hs
		676855 RPB2_HUMAN (1-1167): 0: 1696: 100.00		RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00
+	Hs
		677063 RPB2_HUMAN (1-1167): 0: 1696: 100.00		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72
+	Sp
		145817 RPB2_SCHPO (1-1166): 0: 1485: 59.92		RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42
+	Sc
		440009 RPB2_YEAST (3-1166): 0: 1469: 58.26		RPB7_YEAST (1-171): 4.45e-63: 193: 42.78
+	Hs
		913966 RPC2_HUMAN (11-1165): 0: 1361: 37.14		RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00
+	Hs
		1347030 RPC2_HUMAN (11-1165): 0: 1361: 37.14		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72
+	Dm
		627154 RPC2_DROME (5-1165): 0: 1316: 36.07		Q9VTL6_DROME (1-157): 1.99e-51: 166: 17.79
+	Sc
		606613 RPC2_YEAST (12-1164): 0: 1312: 36.09		RPC8_YEAST (1-158): 1.07e-49: 160: 19.39
+	Pf
		1257374 Q8U0M3_PYRFU (13-1164): 0: 1286: 40.29		Q8U439_PYRFU (1-170): 1.73e-47: 154: 20.23
+	Hs
		913957 RPA2_HUMAN (29-1167): 0: 1199: 28.34		RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00
+	Hs
		1334528 RPA2_HUMAN (29-1167): 0: 1199: 28.34		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72