HitPredict

Interactor 1: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 986 Hs			1 445
+	Hs
		428109 EPHA4_HUMAN (1-986): 0: 1293: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		872702 EPHA4_HUMAN (1-986): 0: 1293: 100.00		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		381152 EPHA4_HUMAN (1-986): 0: 1293: 100.00		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		872701 EPHA4_HUMAN (1-986): 0: 1293: 100.00		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		428222 EPHA7_HUMAN (5-986): 0: 1212: 62.37		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		1072512 EPHA7_HUMAN (5-986): 0: 1212: 62.37		TBB8_HUMAN (1-427): 0: 704: 91.10
+	Hs
		411272 INSR_HUMAN (284-902): 1.29e-145: 470: 25.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		537737 INSRR_HUMAN (285-927): 4.48e-140: 453: 25.49		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		435747 IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		427991 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		TBB5_HUMAN (1-429): 0: 711: 98.37