HitPredict

Interactor 1: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Interactor 2: GOPC (Q9HD26)
Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST)
Gene: GOPC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 986 Hs			1 462
+	Hs
		1072604 EPHA7_HUMAN (5-986): 0: 1212: 62.37		GOPC_HUMAN (1-462): 5.03e-116: 350: 100.00
+	Hs
		872493 EPHA5_HUMAN (2-986): 0: 1201: 63.67		GOPC_HUMAN (1-462): 5.03e-116: 350: 100.00
+	Hs
		665433 EPHA3_HUMAN (26-986): 0: 1182: 63.01		GOPC_HUMAN (1-462): 5.03e-116: 350: 100.00
+	Hs
		872718 EPHA4_HUMAN (1-986): 0: 1293: 100.00		LIN7C_HUMAN (280-393): 4.65e-35: 131: 38.60
+	Hs
		872638 EPHA4_HUMAN (1-986): 0: 1293: 100.00		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		872678 EPHA4_HUMAN (1-986): 0: 1293: 100.00		LNX1_HUMAN (163-462): 4.74e-22: 101: 13.14
+	Hs
		872679 EPHA4_HUMAN (1-986): 0: 1293: 100.00		PARD3_HUMAN (223-458): 8e-22: 100: 19.84
+	Hs
		872669 EPHA4_HUMAN (1-986): 0: 1293: 100.00		MAGI2_HUMAN (217-433): 9.23e-12: 69.6: 14.67
+	Hs
		1072612 EPHA7_HUMAN (5-986): 0: 1212: 62.37		LIN7C_HUMAN (280-393): 4.65e-35: 131: 38.60
+	Hs
		872496 EPHA5_HUMAN (2-986): 0: 1201: 63.67		LIN7C_HUMAN (280-393): 4.65e-35: 131: 38.60
+	Hs
		1020163 EPHA7_HUMAN (5-986): 0: 1212: 62.37		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		1072558 EPHA7_HUMAN (5-986): 0: 1212: 62.37		LNX1_HUMAN (163-462): 4.74e-22: 101: 13.14
+	Hs
		1072560 EPHA7_HUMAN (5-986): 0: 1212: 62.37		PARD3_HUMAN (223-458): 8e-22: 100: 19.84
+	Hs
		872431 EPHA5_HUMAN (2-986): 0: 1201: 63.67		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		1072546 EPHA7_HUMAN (5-986): 0: 1212: 62.37		LNX2_HUMAN (256-461): 1.4e-18: 90.5: 18.22
+	Hs
		872464 EPHA5_HUMAN (2-986): 0: 1201: 63.67		PARD3_HUMAN (223-458): 8e-22: 100: 19.84
+	Hs
		665393 EPHA3_HUMAN (26-986): 0: 1182: 63.01		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		665414 EPHA3_HUMAN (26-986): 0: 1182: 63.01		PARD3_HUMAN (223-458): 8e-22: 100: 19.84
+	Hs
		665589 EPHB2_HUMAN (30-983): 0: 1169: 58.47		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		665633 EPHB2_HUMAN (30-983): 0: 1169: 58.47		LNX1_HUMAN (163-462): 4.74e-22: 101: 13.14