HitPredict

Interactor 1: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Interactor 2: RSP14 (Q9UHP6)
Radial spoke head 14 homolog (Rhabdoid tumor deletion region protein 1)
Gene: RSPH14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 986 Hs			1 348
+	Hs
		542244 EPHA4_HUMAN (1-986): 0: 1293: 100.00		PLAK_HUMAN (28-210): 9.62e-10: 62.1: 13.66
+	Hs
		542333 EPHA7_HUMAN (5-986): 0: 1212: 62.37		PLAK_HUMAN (28-210): 9.62e-10: 62.1: 13.66
+	Hs
		717105 EPHA7_HUMAN (5-986): 0: 1212: 62.37		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34
+	Hs
		542243 EPHA5_HUMAN (2-986): 0: 1201: 63.67		PLAK_HUMAN (28-210): 9.62e-10: 62.1: 13.66
+	Hs
		716907 EPHA5_HUMAN (2-986): 0: 1201: 63.67		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34
+	Hs
		542198 EPHB2_HUMAN (30-983): 0: 1169: 58.47		PLAK_HUMAN (28-210): 9.62e-10: 62.1: 13.66
+	Hs
		665553 EPHB2_HUMAN (30-983): 0: 1169: 58.47		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34
+	Hs
		665443 EPHA8_HUMAN (30-981): 0: 1107: 57.11		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34
+	Hs
		853217 EPHB4_HUMAN (14-977): 0: 1028: 49.90		IMA1_HUMAN (16-255): 2.11e-26: 111: 12.30
+	Hs
		131383 EPHA2_HUMAN (27-986): 0: 1059: 50.36		IMA4_HUMAN (16-184): 7.7e-10: 61.9: 9.59
+	Hs
		665156 EPHA2_HUMAN (27-986): 0: 1059: 50.36		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34
+	Dm
		578636 Q0KIF4_DROME (25-974): 0: 894: 41.08		ARM_DROME (12-302): 1.08e-19: 92.2: 16.21
+	At
		1278234 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		PUB13_ARATH (146-343): 2.26e-31: 126: 22.28
+	Mm
		546270 INSR_MOUSE (284-952): 1.38e-146: 472: 24.38		PLAK_MOUSE (28-210): 7.63e-10: 62.1: 13.66
+	Hs
		542203 UFO_HUMAN (268-928): 5.13e-150: 469: 23.72		PLAK_HUMAN (28-210): 9.62e-10: 62.1: 13.66
+	Rn
		544931 INSR_RAT (284-952): 7.97e-144: 465: 24.14		CTNB1_RAT (7-138): 9.96e-10: 61.9: 12.34
+	Hs
		435524 IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47		PLAK_HUMAN (28-210): 9.62e-10: 62.1: 13.66
+	Hs
		435557 IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34
+	Hs
		412054 FYN_HUMAN (615-879): 2.51e-66: 234: 44.20		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34
+	Hs
		522819 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		CTNB1_HUMAN (7-138): 1.02e-09: 61.9: 12.34