HitPredict

Interactor 1: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.853

Property	Details
Experiments	18158899, 31263106, 20595233
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 914 Sc			1 136
+	Sc
		416319 SIR3_YEAST (1-914): 0: 587: 26.50		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		416300 SIR3_YEAST (1-914): 0: 587: 26.50		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		217792 ORC4_HUMAN (443-840): 4.19e-80: 268: 13.51		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		217794 ORC4_HUMAN (443-840): 4.19e-80: 268: 13.51		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		217808 ORC4_HUMAN (443-840): 4.19e-80: 268: 13.51		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Zm
		16673 A0A1D6GQ42_MAIZE (420-688): 1.21e-26: 119: 11.68		B6SIV8_MAIZE (1-136): 1.41e-60: 184: 87.50
+	Hs
		874825 TERA_HUMAN (420-667): 3.72e-25: 114: 10.00		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		177487 NVL_HUMAN (333-647): 1.07e-20: 100: 13.68		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		722213 RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		722215 RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		722192 RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73