Interactor 1: PROA (P54885)
Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (GSA dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)
Gene: PRO2

Interactor 2: PROA (P54885)
Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (GSA dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)
Gene: PRO2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 18467557
Identification Methods protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aldedh~Aldedh
Common GO terms GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006561 - proline biosynthetic process
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 456
Sc

1 456
+ Ec
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ At
+ Sc
+ Hs
+ Dr
+ Sc
+ Sc

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Last updated: 15 Jul 2024