HitPredict

Interactor 1: SNAA (P54920)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Gene: NAPA

Interactor 2: SCFD1 (Q8WVM8)
Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)
Gene: SCFD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	30833792, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0019905 - syntaxin binding GO:0044877 - protein-containing complex binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 642
+	Dm
		1095552 SNAP_DROME (5-295): 7.84e-105: 308: 61.51		SLY1_DROME (13-642): 0: 572: 56.81
+	Hs
		1261620 SNAG_HUMAN (4-265): 6.75e-68: 215: 23.40		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		119619 SNAA_HUMAN (1-295): 2.13e-113: 330: 100.00		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		873586 SNAA_HUMAN (1-295): 2.13e-113: 330: 100.00		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Dm
		1096643 Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49		SLY1_DROME (13-642): 0: 572: 56.81
+	Dm
		1096648 Q9VH25_DROME (18-265): 1.8e-53: 177: 17.53		SLY1_DROME (13-642): 0: 572: 56.81
+	Sc
		605788 SEC17_YEAST (8-294): 4.63e-88: 266: 34.48		SLY1_YEAST (1-640): 7.62e-163: 483: 31.55
+	Hs
		1306207 SNAG_HUMAN (4-265): 6.75e-68: 215: 23.40		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Sc
		696571 SEC17_YEAST (8-294): 4.63e-88: 266: 34.48		VPS45_YEAST (33-638): 1.86e-126: 387: 18.03