HitPredict

Interactor 1: SNAA (P54920)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Gene: NAPA

Interactor 2: SNAG (Q99747)
Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma)
Gene: NAPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	30833792, 35271311, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~SNAP
Common GO terms	GO:0005483 - soluble NSF attachment protein activity GO:0006886 - intracellular protein transport GO:0006891 - intra-Golgi vesicle-mediated transport GO:0019905 - syntaxin binding GO:0061025 - membrane fusion and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 312
+	Hs
		1306204 SNAB_HUMAN (1-292): 6.03e-113: 329: 84.25		SNAG_HUMAN (1-312): 3.66e-87: 265: 100.00
+	Hs
		873577 SNAA_HUMAN (1-295): 2.13e-113: 330: 100.00		SNAB_HUMAN (3-281): 7.17e-68: 215: 21.11
+	Dm
		1095569 SNAP_DROME (5-295): 7.84e-105: 308: 61.51		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Dm
		1095576 SNAP_DROME (5-295): 7.84e-105: 308: 61.51		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66
+	Dm
		1353735 Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Dm
		1353741 Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66