HitPredict

Interactor 1: PSMD4 (P55034)
26S proteasome non-ATPase regulatory subunit 4 homolog (26S proteasome regulatory subunit RPN10) (AtRPN10) (26S proteasome regulatory subunit S5A homolog) (Multiubiquitin chain-binding protein 1) (AtMCB1)
Gene: RPN10

Interactor 2: DSK2B (Q9SII8)
Ubiquitin domain-containing protein DSK2b
Gene: DSK2B

Species: Arabidopsis thaliana

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.807

Property	Details
Experiments	26004230, 20059542
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 386 At			1 551
+	Hs
		874198 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		UBQL1_HUMAN (16-548): 2.85e-118: 363: 32.06
+	Hs
		874185 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		UBQL4_HUMAN (7-548): 1.11e-105: 331: 28.85
+	Xl
		1118797 Q4V845_XENLA (1-369): 1.17e-152: 437: 40.56		Q9PVN8_XENLA (3-548): 1.32e-104: 328: 29.34
+	Dm
		874046 PSMD4_DROME (1-380): 1.43e-143: 414: 40.54		Q9VWD9_DROME (18-544): 5.96e-103: 322: 30.40
+	Hs
		874195 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		UBQL2_HUMAN (14-475): 2.48e-86: 281: 30.64
+	At
		874017 PSMD4_ARATH (1-386): 2.73e-178: 502: 100.00		RD23C_ARATH (18-551): 9.28e-61: 208: 16.30
+	At
		874016 PSMD4_ARATH (1-386): 2.73e-178: 502: 100.00		RD23D_ARATH (18-551): 5.71e-53: 186: 15.11
+	At
		874018 PSMD4_ARATH (1-386): 2.73e-178: 502: 100.00		RD23A_ARATH (18-551): 2.57e-48: 173: 14.87
+	At
		874019 PSMD4_ARATH (1-386): 2.73e-178: 502: 100.00		RD23B_ARATH (18-551): 1.48e-46: 168: 15.21
+	Hs
		874117 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		DDI2_HUMAN (18-263): 1.71e-49: 177: 16.41
+	At
		874015 PSMD4_ARATH (1-386): 2.73e-178: 502: 100.00		UBQ3_ARATH (14-94): 5.23e-32: 127: 24.69
+	Hs
		874144 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		DDI1_HUMAN (18-263): 4.65e-46: 168: 19.92
+	Xl
		1118798 Q4V845_XENLA (1-369): 1.17e-152: 437: 40.56		BAG6A_XENLA (12-392): 1.54e-41: 162: 15.05
+	Hs
		474970 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		UBB_HUMAN (14-93): 4.96e-33: 127: 25.00
+	Dm
		874047 PSMD4_DROME (1-380): 1.43e-143: 414: 40.54		Q9VXF9_DROME (18-263): 1.74e-43: 162: 18.25
+	Hs
		874069 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		RL40_HUMAN (18-98): 7.89e-31: 118: 25.93
+	Dm
		874036 PSMD4_DROME (1-380): 1.43e-143: 414: 40.54		Q9VCD5_DROME (18-246): 8.05e-37: 139: 16.60
+	Dm
		547908 PSMD4_DROME (1-380): 1.43e-143: 414: 40.54		RS27A_DROME (18-105): 1.46e-30: 118: 23.86
+	Hs
		874068 PSMD4_HUMAN (1-369): 4.23e-159: 453: 42.93		RS27A_HUMAN (18-105): 1.62e-14: 73: 22.73
+	Sc
		756974 RPN10_YEAST (1-234): 6.42e-102: 304: 45.38		DSK2_YEAST (341-547): 1.98e-32: 130: 24.54