HitPredict

Interactor 1: PSMD4 (P55035)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (54 kDa subunit of mu particle) (Multiubiquitin chain-binding protein) (p54)
Gene: Rpn10

Interactor 2: Q9VCD5 (Q9VCD5)
UV excision repair protein RAD23
Gene: DmelCG10694

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Dm			1 290
+	Rn
		1117345 Q9ESH1_RAT (1-384): 2.79e-175: 495: 53.51		RD23B_RAT (1-289): 1.07e-76: 241: 22.41
+	Hs
		872125 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93
+	Dm
		874035 PSMD4_DROME (1-396): 1.39e-168: 478: 100.00		Q9V3W9_DROME (1-288): 5.54e-64: 208: 22.95
+	Hs
		874198 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		UBQL1_HUMAN (1-258): 7.41e-55: 188: 15.73
+	Hs
		874195 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		UBQL2_HUMAN (1-258): 4.56e-50: 176: 14.61
+	At
		874016 PSMD4_ARATH (1-396): 6.77e-141: 408: 40.44		RD23D_ARATH (1-290): 5.18e-83: 256: 20.96
+	At
		874018 PSMD4_ARATH (1-396): 6.77e-141: 408: 40.44		RD23A_ARATH (1-290): 7.03e-82: 253: 21.74
+	Hs
		874185 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		UBQL4_HUMAN (1-252): 1.75e-45: 163: 13.61
+	At
		874019 PSMD4_ARATH (1-396): 6.77e-141: 408: 40.44		RD23B_ARATH (1-290): 9.96e-79: 245: 21.83
+	Dm
		874046 PSMD4_DROME (1-396): 1.39e-168: 478: 100.00		Q9VWD9_DROME (1-251): 9.47e-42: 152: 15.00
+	Hs
		474970 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		UBB_HUMAN (1-78): 9.01e-32: 119: 26.92
+	Hs
		874068 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		RS27A_HUMAN (1-90): 2.72e-31: 115: 26.67
+	Hs
		874069 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		RL40_HUMAN (1-83): 4.1e-31: 114: 26.51
+	Hs
		872242 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		RD23B_HUMAN (1-245): 4.62e-21: 94.1: 18.70
+	At
		874024 PSMD4_ARATH (1-396): 6.77e-141: 408: 40.44		DSK2B_ARATH (1-248): 6.15e-52: 179: 16.60
+	Ce
		247744 PSMD4_CAEEL (1-375): 4.05e-118: 348: 38.52		Q23451_CAEEL (1-288): 2.07e-67: 214: 24.61
+	Dm
		547908 PSMD4_DROME (1-396): 1.39e-168: 478: 100.00		RS27A_DROME (1-90): 7.15e-16: 75.1: 26.67
+	At
		874015 PSMD4_ARATH (1-396): 6.77e-141: 408: 40.44		UBQ3_ARATH (1-79): 9.44e-31: 118: 25.32
+	At
		874017 PSMD4_ARATH (1-396): 6.77e-141: 408: 40.44		RD23C_ARATH (1-172): 3.21e-21: 94.5: 15.61
+	Zm
		22892 A0A1D6KBS7_MAIZE (1-276): 1.09e-109: 327: 41.64		A0A1D6I428_MAIZE (1-148): 4.26e-35: 133: 17.75