HitPredict

Interactor 1: PSMD4 (P55035)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (54 kDa subunit of mu particle) (Multiubiquitin chain-binding protein) (p54)
Gene: Rpn10

Interactor 2: Q9VK14 (Q9VK14)
Proteasome subunit alpha type
Gene: Prosalpha6T

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 396 Dm			1 289
+	Hs
		637371 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19
+	Hs
		637658 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41
+	Hs
		156262 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		PSA7_HUMAN (6-233): 9.24e-96: 284: 35.93
+	Hs
		656250 Q5VWC4_HUMAN (1-384): 1.7e-175: 495: 54.03		PSA5_HUMAN (1-235): 9.39e-95: 281: 29.34
+	Hs
		638147 Q5VWC4_HUMAN (1-384): 1.7e-175: 495: 54.03		PSA4_HUMAN (1-232): 6.37e-94: 279: 28.87
+	Hs
		656185 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		PSA5_HUMAN (1-235): 9.39e-95: 281: 29.34
+	Hs
		893687 Q5VWC4_HUMAN (1-384): 1.7e-175: 495: 54.03		PSA6_HUMAN (1-239): 4.74e-94: 279: 28.34
+	Hs
		638097 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		PSA4_HUMAN (1-232): 6.37e-94: 279: 28.87
+	Hs
		874058 PSMD4_HUMAN (1-384): 1.25e-174: 493: 53.51		PSA6_HUMAN (1-239): 4.74e-94: 279: 28.34
+	Sc
		756940 RPN10_YEAST (1-225): 2.03e-99: 298: 42.37		PSA6_YEAST (1-232): 2.68e-100: 294: 46.58
+	Sc
		619358 RPN10_YEAST (1-225): 2.03e-99: 298: 42.37		PSA3_YEAST (1-227): 1.62e-32: 122: 32.63