HitPredict

Interactor 1: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Interactor 2: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

The method score is based on:

Property	Details
Experiments	28292943, 27114451, 16990800
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	UIM~UIM, VWA_2~VWA_2
Common GO terms	GO:0000502 - proteasome complex GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 5 others more... GO:0008540 - proteasome regulatory particle, base subcomplex GO:0022624 - proteasome accessory complex GO:0031593 - polyubiquitin modification-dependent protein binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0060090 - molecular adaptor activity
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	377
Hs

1	377

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024