HitPredict

Interactor 1: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Interactor 2: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29378950, 38270169
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 391
+	Hs
		56683 PIPSL_HUMAN (3-364): 0: 532: 92.54		ARRD2_HUMAN (2-383): 5.07e-124: 365: 37.85
+	Hs
		874142 PSMD4_HUMAN (1-364): 0: 530: 100.00		ARRD2_HUMAN (2-383): 5.07e-124: 365: 37.85
+	Hs
		874138 PSMD4_HUMAN (1-364): 0: 530: 100.00		ARRD4_HUMAN (5-383): 9.16e-123: 362: 43.99
+	Dm
		874040 PSMD4_DROME (1-359): 6.74e-149: 428: 57.40		Q9VGU4_DROME (9-307): 1.81e-68: 226: 17.95