HitPredict

Interactor 1: NR1H2 (P55055)
Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor NER) (Nuclear receptor subfamily 1 group H member 2) (Ubiquitously-expressed nuclear receptor)
Gene: NR1H2

Interactor 2: COR2A (Q92828)
Coronin-2A (IR10) (WD repeat-containing protein 2)
Gene: CORO2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.50	0.503

Property	Details
Experiments	21331046
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 460 Hs			1 525
+	Hs
		370696 ESR1_HUMAN (3-459): 2.92e-103: 321: 21.06		COR1C_HUMAN (4-472): 2.38e-118: 358: 42.68
+	Hs
		369932 ESR1_HUMAN (3-459): 2.92e-103: 321: 21.06		WDR5B_HUMAN (1-253): 4.56e-57: 195: 13.85
+	Hs
		369305 ESR1_HUMAN (3-459): 2.92e-103: 321: 21.06		WDR5_HUMAN (1-253): 3.62e-56: 192: 15.00
+	Hs
		488008 RARA_HUMAN (12-460): 1.74e-104: 320: 28.83		SNR40_HUMAN (120-426): 1.89e-54: 189: 15.97
+	Hs
		782513 HNF4A_HUMAN (39-456): 2.18e-103: 317: 22.67		WDR5_HUMAN (1-253): 3.62e-56: 192: 15.00
+	Mm
		903664 ERR2_MOUSE (10-459): 1.4e-99: 306: 19.96		WDR5_MOUSE (1-253): 3.62e-56: 192: 15.00
+	Hs
		740487 PPARG_HUMAN (12-457): 2.74e-97: 303: 24.50		WDR5_HUMAN (1-253): 3.62e-56: 192: 15.00
+	Hs
		490098 COT1_HUMAN (5-456): 1.16e-105: 322: 23.13		RBBP4_HUMAN (131-368): 1.11e-24: 108: 14.40
+	Hs
		369483 ESR1_HUMAN (3-459): 2.92e-103: 321: 21.06		RBBP4_HUMAN (131-368): 1.11e-24: 108: 14.40
+	Hs
		369695 ESR1_HUMAN (3-459): 2.92e-103: 321: 21.06		RBBP7_HUMAN (131-351): 6.33e-25: 108: 13.33
+	Mm
		1141930 ERR2_MOUSE (10-459): 1.4e-99: 306: 19.96		RBBP4_MOUSE (131-368): 1.11e-24: 108: 14.40
+	Hs
		370377 ESR1_HUMAN (3-459): 2.92e-103: 321: 21.06		TBL1R_HUMAN (80-222): 7.12e-13: 72.8: 29.14
+	Hs
		488022 RARA_HUMAN (12-460): 1.74e-104: 320: 28.83		TBL1R_HUMAN (80-222): 7.12e-13: 72.8: 29.14
+	Hs
		370309 ESR1_HUMAN (3-459): 2.92e-103: 321: 21.06		TBL1Y_HUMAN (80-222): 1.53e-12: 71.6: 29.80
+	Hs
		245574 HNF4A_HUMAN (39-456): 2.18e-103: 317: 22.67		TBL1X_HUMAN (80-222): 4.96e-13: 73.6: 30.46
+	Hs
		245556 THB_HUMAN (24-457): 9.01e-102: 313: 27.23		TBL1X_HUMAN (80-222): 4.96e-13: 73.6: 30.46
+	Hs
		500505 THB_HUMAN (24-457): 9.01e-102: 313: 27.23		TBL1R_HUMAN (80-222): 7.12e-13: 72.8: 29.14
+	Xl
		546250 THAA_XENLA (61-460): 3.8e-99: 305: 26.62		TB1RA_XENLA (80-222): 9.63e-13: 72.4: 29.14
+	Hs
		245573 PPARG_HUMAN (12-457): 2.74e-97: 303: 24.50		TBL1X_HUMAN (80-222): 4.96e-13: 73.6: 30.46
+	Hs
		740596 PPARG_HUMAN (12-457): 2.74e-97: 303: 24.50		TBL1R_HUMAN (80-222): 7.12e-13: 72.8: 29.14