HitPredict

Interactor 1: XPO2 (P55060)
Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter)
Gene: CSE1L

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CAS_CSE1~Ras, Cse1~Ras, IBN_N~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 971 Hs			1 193
+	Hs
		874486 XPO2_HUMAN (1-971): 0: 784: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		874474 XPO2_HUMAN (1-971): 0: 784: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		874482 XPO2_HUMAN (1-971): 0: 784: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120366 XPO2_HUMAN (1-971): 0: 784: 100.00		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		178144 IPO8_HUMAN (7-962): 1.26e-161: 503: 18.13		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		312238 IPO7_HUMAN (7-880): 9.51e-158: 493: 19.02		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		925496 TNPO1_HUMAN (2-861): 1.05e-127: 410: 13.35		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		901027 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		900811 IPO9_HUMAN (8-923): 1.04e-112: 373: 14.79		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		951442 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		894563 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		951243 IPO9_HUMAN (8-923): 1.04e-112: 373: 14.79		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		894326 IPO9_HUMAN (8-923): 1.04e-112: 373: 14.79		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		127230 IPO5_HUMAN (90-886): 1.85e-18: 93.4: 11.41		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33