HitPredict

Interactor 1: XPO2 (P55060)
Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter)
Gene: CSE1L

Interactor 2: GPR17 (Q13304)
Uracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor) (G-protein coupled receptor 17) (P2Y-like receptor) (R12)
Gene: GPR17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 971 Hs			1 367
+	Hs
		874515 XPO2_HUMAN (1-971): 0: 784: 100.00		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		178157 IPO8_HUMAN (7-962): 1.26e-161: 503: 18.13		GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00
+	Hs
		178124 IPO8_HUMAN (7-962): 1.26e-161: 503: 18.13		P2RY2_HUMAN (51-331): 2.74e-84: 262: 33.91
+	Hs
		178120 IPO8_HUMAN (7-962): 1.26e-161: 503: 18.13		APJ_HUMAN (32-364): 1.02e-69: 224: 27.79
+	Hs
		155568 TNPO2_HUMAN (1-861): 4.17e-128: 411: 12.97		GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00
+	Hs
		178136 IPO8_HUMAN (7-962): 1.26e-161: 503: 18.13		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78
+	Hs
		1031108 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00
+	Hs
		849717 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		CCR6_HUMAN (57-366): 1.61e-84: 262: 26.63
+	Hs
		178209 IPO8_HUMAN (7-962): 1.26e-161: 503: 18.13		P2RY8_HUMAN (66-365): 1.26e-33: 129: 30.77
+	Hs
		178168 IPO8_HUMAN (7-962): 1.26e-161: 503: 18.13		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		312275 IPO7_HUMAN (7-880): 9.51e-158: 493: 19.02		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		723119 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		OPRM_HUMAN (9-365): 4.73e-73: 234: 21.04
+	Hs
		666357 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		NK3R_HUMAN (2-367): 7.33e-69: 225: 18.33
+	Hs
		723430 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		APJ_HUMAN (32-364): 1.02e-69: 224: 27.79
+	Hs
		155548 TNPO2_HUMAN (1-861): 4.17e-128: 411: 12.97		LPAR6_HUMAN (48-336): 8.83e-47: 164: 32.22
+	Hs
		155556 TNPO2_HUMAN (1-861): 4.17e-128: 411: 12.97		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78
+	Hs
		126557 TNPO2_HUMAN (1-861): 4.17e-128: 411: 12.97		P2Y10_HUMAN (61-336): 5.39e-40: 146: 35.69
+	Hs
		798459 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		LPAR6_HUMAN (48-336): 8.83e-47: 164: 32.22
+	Hs
		1067562 TNPO1_HUMAN (2-861): 1.05e-127: 410: 13.35		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		876208 IPO11_HUMAN (1-966): 7.87e-116: 380: 15.29		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78