HitPredict

Interactor 1: NCAN (P55067)
Neurocan core protein (245 kDa early postnatal core glycoprotein) (Chondroitin sulfate proteoglycan 3) [Cleaved into: 150 kDa adult core glycoprotein]
Gene: NCAN

Interactor 2: ITM2B (Q5XIE8)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29476059
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1257 Rn			1 266
+	Rn
		102552 G3V8R2_RAT (1-1257): 0: 810: 99.13		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		372928 HPLN1_RAT (10-341): 1.68e-137: 424: 37.10		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		1140311 HPLN2_RAT (10-341): 9.95e-105: 336: 38.10		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		1140308 CSPG2_RAT (529-1240): 1e-75: 279: 28.61		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		874726 PGCB_RAT (640-1244): 4.37e-47: 185: 26.44		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		431431 PGCA_RAT (325-1238): 8.03e-42: 170: 20.32		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Hs
		1357145 CLC4E_HUMAN (1014-1151): 8.57e-44: 160: 28.86		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24
+	Hs
		1263932 CLC4D_HUMAN (1026-1150): 1.98e-43: 159: 31.54		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24
+	Hs
		1343942 CLC4E_HUMAN (1014-1151): 8.57e-44: 160: 28.86		ITM2C_HUMAN (1-265): 1.17e-121: 349: 42.75
+	Hs
		1263913 CLC4D_HUMAN (1026-1150): 1.98e-43: 159: 31.54		ITM2C_HUMAN (1-265): 1.17e-121: 349: 42.75