HitPredict

Interactor 1: C9JN51 (C9JN51)
NF-kappa-B essential modulator
Gene: IKBKG

Interactor 2: M3K14 (Q99558)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)
Gene: MAP3K14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30833792
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 947
+	Hs
		1304549 NEMO_HUMAN (1-250): 2.95e-105: 312: 100.00		M3K14_HUMAN (1-947): 0: 799: 100.00
+	Hs
		87259 C9J2V2_HUMAN (13-250): 6.98e-98: 293: 100.00		M3K14_HUMAN (1-947): 0: 799: 100.00
+	Hs
		682095 NEMO_HUMAN (1-250): 2.95e-105: 312: 100.00		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Mm
		291781 NEMO_MOUSE (1-248): 1.72e-101: 302: 88.71		AKT1_MOUSE (286-713): 1.66e-131: 406: 20.22
+	Hs
		117041 NEMO_HUMAN (1-250): 2.95e-105: 312: 100.00		SGK1_HUMAN (354-729): 7.08e-116: 363: 21.19
+	Hs
		862010 NEMO_HUMAN (1-250): 2.95e-105: 312: 100.00		PLK1_HUMAN (406-781): 1.04e-106: 345: 26.87
+	Hs
		1377415 NEMO_HUMAN (1-250): 2.95e-105: 312: 100.00		M3K2_HUMAN (386-626): 1.28e-24: 112: 33.60
+	Hs
		1306411 NEMO_HUMAN (1-250): 2.95e-105: 312: 100.00		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Mm
		101503 NEMO_MOUSE (1-248): 1.72e-101: 302: 88.71		F8VQ72_MOUSE (370-643): 4.83e-24: 111: 30.52