Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: UBXN6 (Q9BZV1)
UBX domain-containing protein 6 (UBX domain-containing protein 1)
Gene: UBXN6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 26186194, 26475856, 26389662, 27913212, 28514442, 29997244, 27753622, 31847414, 33961781, 19174149, 35389758, 21896481, 18775313, 16807242, 19275885, 22350894, 22337587, 25078495, 27762274, 27561680 and 8 others

more...

Identification Methods affinity chromatography technology, pull down, fluorescent resonance energy transfer, unspecified method, two hybrid, proximity labelling technology, luminescence based mammalian interactome mapping, molecular sieving, two hybrid array, two hybrid pooling approach and 3 others

more...

Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC48_2~UBX, CDC48_N~UBX
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016236 - macroautophagy
GO:0032510 - endosome to lysosome transport via multivesicular body sorting pathway
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 806
Hs

1 441
+ Dm
+ Ce
+ Ce
+ Hs
+ At
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024