HitPredict

Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: SPRTN (Q9H040)
DNA-dependent metalloprotease SPRTN (EC 3.4.24.-) (DNA damage protein targeting VCP) (DVC1) (Protein with SprT-like domain at the N terminus) (Spartan)
Gene: SPRTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.743

The method score is based on:

Property Details
Experiments 35469923, 22902628, 31477623, 33567341, 33558481, 23042607, 23042605
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0019985 - translesion synthesis
GO:0031593 - polyubiquitin modification-dependent protein binding
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 806
Hs

1 489
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024