Interactor 1: AK1BF (C9JRZ8)
Aldo-keto reductase family 1 member B15 (EC 1.1.1.-) (EC 1.1.1.300) (EC 1.1.1.54) (Estradiol 17-beta-dehydrogenase AKR1B15) (Farnesol dehydrogenase) (EC 1.1.1.216) (Testosterone 17beta-dehydrogenase) (EC 1.1.1.64)
Gene: AKR1B15

Interactor 2: ALDR (P15121)
Aldo-keto reductase family 1 member B1 (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldose reductase) (AR) (EC 1.1.1.21)
Gene: AKR1B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.848

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aldo_ket_red~Aldo_ket_red
Common GO terms GO:0004032 - aldose reductase (NADPH) activity
GO:0005829 - cytosol
GO:0047655 - allyl-alcohol dehydrogenase activity
GO:0052650 - all-trans-retinol dehydrogenase (NADP+) activity
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 316
Hs

1 316
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024