HitPredict

Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29540532, 30442662
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0031593 - polyubiquitin modification-dependent protein binding and 1 others more... GO:0036503 - ERAD pathway
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 624
+	Hs
		875428 TERA_HUMAN (1-806): 0: 749: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		803456 TERA_HUMAN (1-806): 0: 749: 100.00		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		874796 TERA_HUMAN (1-806): 0: 749: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		874795 TERA_HUMAN (1-806): 0: 749: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		87551 C9JUP7_HUMAN (46-806): 0: 707: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Sp
		1013615 CDC48_SCHPO (10-806): 0: 699: 70.30		DSK2_SCHPO (33-240): 1.27e-27: 116: 23.26
+	Dm
		547928 TERA_DROME (5-806): 0: 734: 82.96		RS27A_DROME (33-103): 6.99e-13: 68.4: 33.33
+	Hs
		218082 PEX1_HUMAN (6-424): 6.61e-62: 229: 27.99		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		218001 PEX1_HUMAN (6-424): 6.61e-62: 229: 27.99		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86