Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 16275660, 29599191, 17872946, 35961308, 15331598, 20126661, 17311810, 21914798, 23383273, 23333620, 24100225, 22119785, 26424800, 28301499, 27387505, 18835813, 17681147, 16186510, 19828134, 21343306 and 5 others

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Identification Methods two hybrid, pull down, affinity chromatography technology, x-ray crystallography, unspecified method, anti bait coimmunoprecipitation, filter binding, anti tag coimmunoprecipitation, fluorescence microscopy
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0030968 - endoplasmic reticulum unfolded protein response
and 6 others

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Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 806
Hs

1 643
+ Mm
+ Hs
+ Sp
+ Sc
+ Hs
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024