HitPredict

Interactor 1: C9JWJ8 (C9JWJ8)
Nuclear factor 1
Gene: NFIX

Interactor 2: FOXC1 (Q12948)
Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)
Gene: FOXC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25609649
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 460 Hs			1 553
+	Hs
		1021110 NFIX_HUMAN (3-460): 4.08e-172: 494: 90.98		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		1018216 NFIA_HUMAN (3-460): 7.4e-139: 410: 63.14		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		964183 NFIX_HUMAN (3-460): 4.08e-172: 494: 90.98		FOXK2_HUMAN (19-481): 4.43e-47: 176: 22.18
+	Hs
		443179 NFIC_HUMAN (3-460): 1.35e-131: 391: 52.86		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		135114 NFIB_HUMAN (3-460): 3.45e-130: 384: 52.07		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		877734 NFIX_HUMAN (3-460): 4.08e-172: 494: 90.98		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		1018217 NFIA_HUMAN (3-460): 7.4e-139: 410: 63.14		FOXI1_HUMAN (40-316): 2.07e-45: 166: 35.02
+	Hs
		1018218 NFIA_HUMAN (3-460): 7.4e-139: 410: 63.14		FOXL1_HUMAN (42-371): 4.37e-45: 164: 30.42
+	Hs
		1018259 NFIA_HUMAN (3-460): 7.4e-139: 410: 63.14		FOXC2_HUMAN (1-553): 7.96e-44: 164: 37.46
+	Hs
		126421 NFIC_HUMAN (3-460): 1.35e-131: 391: 52.86		FOXE1_HUMAN (54-390): 3.86e-46: 167: 31.66
+	Hs
		443180 NFIC_HUMAN (3-460): 1.35e-131: 391: 52.86		FOXI1_HUMAN (40-316): 2.07e-45: 166: 35.02
+	Hs
		443181 NFIC_HUMAN (3-460): 1.35e-131: 391: 52.86		FOXL1_HUMAN (42-371): 4.37e-45: 164: 30.42
+	Hs
		135115 NFIB_HUMAN (3-460): 3.45e-130: 384: 52.07		FOXI1_HUMAN (40-316): 2.07e-45: 166: 35.02
+	Hs
		877715 NFIA_HUMAN (3-460): 7.4e-139: 410: 63.14		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		135116 NFIB_HUMAN (3-460): 3.45e-130: 384: 52.07		FOXL1_HUMAN (42-371): 4.37e-45: 164: 30.42
+	Hs
		443157 NFIC_HUMAN (3-460): 1.35e-131: 391: 52.86		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		135098 NFIB_HUMAN (3-460): 3.45e-130: 384: 52.07		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Ce
		1088828 NFI1_CAEEL (7-372): 2.54e-98: 314: 31.08		PHA4_CAEEL (33-322): 7.46e-40: 153: 29.20
+	Ce
		1014615 NFI1_CAEEL (7-372): 2.54e-98: 314: 31.08		FKH6_CAEEL (62-362): 6.74e-38: 144: 28.53
+	Hs
		877807 KMT2C_HUMAN (191-454): 3.54e-09: 61.5: 12.03		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52