HitPredict

Interactor 1: PAR2 (P55085)
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
Gene: F2RL1

Interactor 2: AT2C1 (P98194)
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) (SPCA1)
Gene: ATP2C1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 397 Hs			1 919
+	Hs
		849663 CCR6_HUMAN (72-394): 3.15e-79: 250: 23.57		AT2C1_HUMAN (1-919): 0: 865: 100.00
+	Hs
		958300 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		AT2C1_HUMAN (1-919): 0: 865: 100.00
+	Hs
		530862 CXCR4_HUMAN (73-370): 5.97e-81: 254: 22.62		AT1A3_HUMAN (10-905): 0: 801: 25.86
+	Hs
		530845 P2RY2_HUMAN (67-394): 2.77e-79: 250: 26.71		AT1A3_HUMAN (10-905): 0: 801: 25.86
+	Hs
		530883 GPR17_HUMAN (57-367): 8.1e-79: 249: 29.02		AT1A3_HUMAN (10-905): 0: 801: 25.86
+	Hs
		530923 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		AT1A3_HUMAN (10-905): 0: 801: 25.86
+	Hs
		530861 PAR2_HUMAN (1-374): 1.43e-74: 239: 100.00		AT1A3_HUMAN (10-905): 0: 801: 25.86
+	Hs
		782452 P2RY2_HUMAN (67-394): 2.77e-79: 250: 26.71		AT2A3_HUMAN (24-903): 0: 785: 31.72
+	Hs
		849697 CCR6_HUMAN (72-394): 3.15e-79: 250: 23.57		AT2A3_HUMAN (24-903): 0: 785: 31.72
+	Hs
		1031036 GPR17_HUMAN (57-367): 8.1e-79: 249: 29.02		AT2A3_HUMAN (24-903): 0: 785: 31.72
+	Hs
		843465 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		AT1A2_HUMAN (16-905): 0: 788: 26.01
+	Hs
		1202701 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		AT2A3_HUMAN (24-903): 0: 785: 31.72
+	Hs
		561533 CCR4_HUMAN (73-392): 3.02e-85: 265: 23.24		AT2A2_HUMAN (24-915): 0: 762: 32.01
+	Hs
		876172 PAR2_HUMAN (1-374): 1.43e-74: 239: 100.00		AT2A3_HUMAN (24-903): 0: 785: 31.72
+	Hs
		561566 GPR17_HUMAN (57-367): 8.1e-79: 249: 29.02		AT2A2_HUMAN (24-915): 0: 762: 32.01
+	Hs
		619207 P2RY2_HUMAN (67-394): 2.77e-79: 250: 26.71		AT2B4_HUMAN (8-913): 0: 759: 23.26
+	Hs
		619214 CCR6_HUMAN (72-394): 3.15e-79: 250: 23.57		AT2B4_HUMAN (8-913): 0: 759: 23.26
+	Hs
		619229 GPR17_HUMAN (57-367): 8.1e-79: 249: 29.02		AT2B4_HUMAN (8-913): 0: 759: 23.26
+	Hs
		619255 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		AT2B4_HUMAN (8-913): 0: 759: 23.26
+	Hs
		561538 PAR2_HUMAN (1-374): 1.43e-74: 239: 100.00		AT2A2_HUMAN (24-915): 0: 762: 32.01