HitPredict

Interactor 1: PAR2 (P55085)
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
Gene: F2RL1

Interactor 2: Q4LE69 (Q4LE69)
1-phosphatidylinositol 4-kinase (EC 2.7.1.67)
Gene: PIK4CA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 2121
+	Hs
		1117762 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		723045 OPRM_HUMAN (5-397): 1.72e-74: 238: 21.66		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		787661 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		787637 PAR2_HUMAN (1-374): 1.43e-74: 239: 100.00		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		723014 OPRM_HUMAN (5-397): 1.72e-74: 238: 21.66		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		723312 APJ_HUMAN (55-383): 7.14e-70: 226: 23.17		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		824703 NPY2R_HUMAN (61-361): 4.07e-68: 221: 16.56		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		723280 APJ_HUMAN (55-383): 7.14e-70: 226: 23.17		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		787633 NPY2R_HUMAN (61-361): 4.07e-68: 221: 16.56		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		126596 P2Y10_HUMAN (60-354): 7.94e-30: 119: 29.90		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		126574 P2Y10_HUMAN (60-354): 7.94e-30: 119: 29.90		PI4KA_HUMAN (49-2121): 0: 2740: 100.00
+	Hs
		787363 CXCR4_HUMAN (73-370): 5.97e-81: 254: 22.62		PK3CB_HUMAN (1465-2118): 7.11e-140: 467: 18.78
+	Hs
		822537 CXCR4_HUMAN (73-370): 5.97e-81: 254: 22.62		PK3CG_HUMAN (1522-2119): 7.16e-133: 448: 19.56
+	Mm
		936867 CXCR4_MOUSE (73-370): 1.59e-80: 253: 22.40		PK3CG_MOUSE (1522-2119): 4.65e-131: 443: 19.87
+	Hs
		128855 P2RY6_HUMAN (76-352): 1.05e-25: 107: 30.07		P3C2A_HUMAN (1411-2120): 1.91e-150: 512: 17.85
+	Hs
		126573 P2Y10_HUMAN (60-354): 7.94e-30: 119: 29.90		PK3CB_HUMAN (1465-2118): 7.11e-140: 467: 18.78
+	Hs
		787392 LPAR5_HUMAN (80-395): 1.57e-28: 116: 28.75		PK3CB_HUMAN (1465-2118): 7.11e-140: 467: 18.78