HitPredict

Interactor 1: TYRO3 (P55144)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Etk2/tyro3) (TK19-2) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Interactor 2: UFO (Q00993)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (Adhesion-related kinase)
Gene: Axl

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18787040
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, Ig_3~fn3, PK_Tyr_Ser-Thr~fn3, I-set~fn3, I-set~Ig_2, Ig_3~I-set, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001618 - virus receptor activity
GO:0001764 - neuron migration
GO:0001779 - natural killer cell differentiation
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005524 - ATP binding
and 23 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 880
Mm

1 888
+ Hs
+ Hs
+ Hs
+ Gg
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024