HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 870
+	Hs
		876363 AFAD_HUMAN (1-1824): 0: 1279: 100.00		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		876420 AFAD_HUMAN (1-1824): 0: 1279: 100.00		DNMBP_HUMAN (7-559): 6.75e-29: 126: 15.27
+	Hs
		297818 AFAD_HUMAN (1-1824): 0: 1279: 100.00		K0754_HUMAN (151-869): 1.64e-27: 122: 10.56
+	Mm
		222888 AFAD_MOUSE (1-1824): 0: 1234: 92.98		ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93
+	Hs
		876457 AFAD_HUMAN (1-1824): 0: 1279: 100.00		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Hs
		882269 KIF1A_HUMAN (183-586): 2.27e-62: 238: 15.40		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		882306 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		231481 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		882585 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		1066880 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79
+	Hs
		302288 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		1066536 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		CHAP1_HUMAN (74-473): 9.49e-21: 100: 15.99
+	Hs
		1066506 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		1066964 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		PCLO_HUMAN (49-739): 1.71e-12: 73.8: 9.65
+	Hs
		1056837 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16
+	Hs
		298003 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		FCSD2_HUMAN (3-156): 3.32e-24: 110: 24.68
+	Hs
		231661 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Mm
		1143451 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		SH3K1_MOUSE (7-359): 4.75e-18: 91: 16.25
+	Mm
		88458 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		D3Z656_MOUSE (314-773): 3.39e-11: 69.6: 10.22
+	Mm
		1143433 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		SYNJ1_MOUSE (341-773): 1.22e-09: 64.5: 9.93