HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	35271311, 36931259, 17979178
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction GO:0045296 - cadherin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 255
+	Hs
		66891 A8MQ02_HUMAN (43-1824): 0: 1196: 99.44		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Sc
		585292 MYO2_YEAST (162-947): 2.18e-95: 343: 12.05		BMH2_YEAST (4-242): 1.14e-134: 382: 77.08
+	Sc
		585268 MYO2_YEAST (162-947): 2.18e-95: 343: 12.05		BMH1_YEAST (2-243): 2.43e-134: 381: 75.72
+	Hs
		910062 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909583 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Dm
		54781 A1ZA18_DROME (184-689): 5.26e-62: 237: 13.76		1433E_DROME (1-254): 2.95e-146: 411: 82.69
+	Hs
		231490 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910260 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		909912 RADIL_HUMAN (830-1106): 4.06e-27: 122: 18.06		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909498 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00