HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression GO:0031267 - small GTPase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 178
+	Hs
		975056 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974827 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		975051 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974978 RADIL_HUMAN (830-1106): 4.06e-27: 122: 18.06		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974816 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		975108 NEB1_HUMAN (1002-1092): 1.04e-19: 98.7: 40.00		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974786 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		231479 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		CAV3_HUMAN (32-178): 1.22e-75: 224: 64.00