HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	9707552, 34079125
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 998
+	Hs
		665569 AFAD_HUMAN (1-1824): 0: 1279: 100.00		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		872402 AFAD_HUMAN (1-1824): 0: 1279: 100.00		EPHB3_HUMAN (29-996): 0: 1113: 55.52
+	Hs
		665186 AFAD_HUMAN (1-1824): 0: 1279: 100.00		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		171297 AFAD_HUMAN (1-1824): 0: 1279: 100.00		EPHB6_HUMAN (32-996): 0: 927: 40.44
+	Hs
		1072604 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1049958 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		872713 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		872493 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		665433 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		EPHA3_HUMAN (25-990): 0: 1189: 62.01
+	Hs
		665663 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		665600 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		600576 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		EPHA1_HUMAN (10-986): 0: 975: 44.30
+	Hs
		665228 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		171337 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		EPHB6_HUMAN (32-996): 0: 927: 40.44
+	Hs
		600564 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		EPHA1_HUMAN (10-986): 0: 975: 44.30
+	Hs
		674422 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		442832 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		HCK_HUMAN (611-891): 2.73e-64: 228: 42.40
+	Hs
		412200 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45
+	Hs
		442887 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		HCK_HUMAN (611-891): 2.73e-64: 228: 42.40
+	Hs
		412128 DLG4_HUMAN (1002-1238): 1.07e-27: 123: 17.51		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45