HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: TRIPB (Q15643)
Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230)
Gene: TRIP11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031267 - small GTPase binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 1979
+	Hs
		876385 AFAD_HUMAN (1-1824): 0: 1279: 100.00		GOGB1_HUMAN (1012-1942): 1.52e-22: 108: 9.80
+	Hs
		876402 AFAD_HUMAN (1-1824): 0: 1279: 100.00		GRDN_HUMAN (168-989): 5.81e-21: 103: 14.83
+	Hs
		876522 AFAD_HUMAN (1-1824): 0: 1279: 100.00		DAPLE_HUMAN (226-893): 3.17e-14: 81.2: 16.59
+	Hs
		725065 MYO5B_HUMAN (102-939): 4.92e-118: 416: 14.72		MYH9_HUMAN (1032-1925): 1.72e-40: 167: 8.66
+	Hs
		725033 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		MYH9_HUMAN (1032-1925): 1.72e-40: 167: 8.66
+	Hs
		724838 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MYH9_HUMAN (1032-1925): 1.72e-40: 167: 8.66
+	Hs
		728480 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MYH11_HUMAN (1478-1959): 1.61e-18: 95.4: 9.49
+	Hs
		725166 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MYH10_HUMAN (1471-1959): 8.55e-18: 92.7: 10.23
+	Hs
		551712 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		DESP_HUMAN (442-1827): 1.01e-14: 82.8: 11.04
+	Hs
		725035 MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60		MYH9_HUMAN (1032-1925): 1.72e-40: 167: 8.66
+	Hs
		725086 MYO5A_HUMAN (1369-1800): 2.36e-11: 71.5: 10.74		MYH9_HUMAN (1032-1925): 1.72e-40: 167: 8.66
+	Hs
		724839 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		MYH9_HUMAN (1032-1925): 1.72e-40: 167: 8.66
+	Dm
		113473 M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95		CL190_DROME (40-988): 1.16e-21: 105: 15.83
+	Dm
		1303380 PATJ_DROME (969-1164): 1.83e-29: 129: 28.08		MYSN_DROME (1192-1785): 5.11e-13: 77: 12.94
+	Mm
		936586 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		ROCK2_MOUSE (289-951): 6.16e-11: 70.1: 20.92
+	Hs
		1068548 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		GRDN_HUMAN (168-989): 5.81e-21: 103: 14.83
+	Hs
		280085 MPDZ_HUMAN (971-1166): 2.25e-13: 78.3: 21.43		DAPLE_HUMAN (226-893): 3.17e-14: 81.2: 16.59