HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: RHG29 (Q52LW3)
Rho GTPase-activating protein 29 (PTPL1-associated RhoGAP protein 1) (Rho-type GTPase-activating protein 29)
Gene: ARHGAP29

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 1261
+	Hs
		253330 AFAD_HUMAN (1-1824): 0: 1279: 100.00		SRGP2_HUMAN (176-1241): 8.39e-126: 416: 13.89
+	Hs
		64675 AFAD_HUMAN (1-1824): 0: 1279: 100.00		RHG32_HUMAN (603-1226): 1.47e-75: 278: 17.39
+	Hs
		876410 AFAD_HUMAN (1-1824): 0: 1279: 100.00		RHG21_HUMAN (529-1114): 2.51e-70: 262: 16.64
+	Hs
		506555 AFAD_HUMAN (1-1824): 0: 1279: 100.00		BCR_HUMAN (668-853): 1.47e-16: 87.8: 32.98
+	Hs
		1020174 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		RHG29_HUMAN (1-1261): 0: 914: 100.00
+	Hs
		253413 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		SRGP2_HUMAN (176-1241): 8.39e-126: 416: 13.89
+	Sc
		585315 MYO2_YEAST (162-947): 2.18e-95: 343: 12.05		RGA1_YEAST (144-885): 8.96e-83: 295: 13.52
+	Hs
		231412 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		SRGP2_HUMAN (176-1241): 8.39e-126: 416: 13.89
+	Hs
		1137461 RAIN_HUMAN (244-982): 5.22e-96: 336: 16.01		RGAP1_HUMAN (299-969): 2.35e-67: 242: 16.72
+	Mm
		1265174 LNX2_MOUSE (973-1126): 6.83e-17: 88.9: 20.38		SRGP2_MOUSE (176-1241): 3.33e-127: 420: 13.80
+	Hs
		253346 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		SRGP2_HUMAN (176-1241): 8.39e-126: 416: 13.89
+	Hs
		1066667 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		RGAP1_HUMAN (299-969): 2.35e-67: 242: 16.72
+	Mm
		1143388 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		RHG32_MOUSE (603-1226): 2.68e-72: 268: 16.79
+	Hs
		856149 RADIL_HUMAN (830-1106): 4.06e-27: 122: 18.06		CHIO_HUMAN (533-886): 6.43e-74: 255: 24.31
+	Hs
		1148381 DLG3_HUMAN (1009-1467): 4.67e-23: 109: 13.25		RHG17_HUMAN (651-1242): 6.82e-74: 266: 16.64
+	Hs
		1271026 DLG3_HUMAN (1009-1467): 4.67e-23: 109: 13.25		RGAP1_HUMAN (299-969): 2.35e-67: 242: 16.72
+	Hs
		1148378 INADL_HUMAN (1003-1089): 2.08e-11: 71.8: 25.81		RHG17_HUMAN (651-1242): 6.82e-74: 266: 16.64
+	Hs
		1133710 MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60		RHG21_HUMAN (529-1114): 2.51e-70: 262: 16.64
+	Hs
		1138024 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		SYDE2_HUMAN (668-857): 1.72e-15: 84.3: 33.50
+	Mm
		1131438 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		ABR_MOUSE (668-867): 9.49e-19: 94.4: 31.68