HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: LIPB1 (Q86W92)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)
Gene: PPFIBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~SAM_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0045296 - cadherin binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 1011
+	Hs
		876412 AFAD_HUMAN (1-1824): 0: 1279: 100.00		MRCKA_HUMAN (50-632): 1.12e-35: 149: 15.57
+	Hs
		1066343 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		725065 MYO5B_HUMAN (102-939): 4.92e-118: 416: 14.72		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		725033 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		724838 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		725166 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MYH10_HUMAN (2-784): 3.65e-29: 128: 8.24
+	Ce
		619840 UN104_CAEEL (183-614): 6.37e-75: 279: 16.34		LIPA_CAEEL (4-657): 3.06e-10: 66.5: 11.04
+	Mm
		1149111 LNX2_MOUSE (973-1126): 6.83e-17: 88.9: 20.38		KAZRN_MOUSE (255-892): 3.05e-63: 231: 21.33
+	Hs
		728480 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MYH11_HUMAN (2-530): 1.42e-16: 87.6: 9.26
+	Dm
		113617 M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95		Q9VU88_DROME (388-928): 2.17e-53: 200: 32.05
+	Hs
		1068563 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		KAZRN_HUMAN (179-892): 1.83e-62: 229: 19.28
+	Mm
		887083 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		ANS1A_MOUSE (365-904): 2.17e-40: 164: 14.47
+	Hs
		725035 MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		725086 MYO5A_HUMAN (1369-1800): 2.36e-11: 71.5: 10.74		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		724839 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Mm
		1143432 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		CACO1_MOUSE (101-568): 8.96e-13: 74.6: 14.58
+	Dr
		71432 NIPLB_DANRE (875-1685): 1.84e-20: 101: 11.31		B3DKC5_DANRE (84-341): 3.17e-11: 69.2: 17.04
+	Hs
		1068591 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		MY18B_HUMAN (45-635): 2.91e-14: 80: 12.13