Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: PTPRU (Q92729)
Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi)
Gene: PTPRU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28675297
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0007155 - cell adhesion
GO:0030336 - negative regulation of cell migration
GO:2000049 - positive regulation of cell-cell adhesion mediated by cadherin
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1824
Hs

1 1446
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ Dm
+ Rn
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+ Dm

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Last updated: 15 Jul 2024