HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: SI1L2 (Q9P2F8)
Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)
Gene: SIPA1L2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 1722
+	Hs
		196421 AFAD_HUMAN (1-1824): 0: 1279: 100.00		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		230226 AFAD_HUMAN (1-1824): 0: 1279: 100.00		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Hs
		196511 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		812870 AFAD_HUMAN (1-1824): 0: 1279: 100.00		RPGP1_HUMAN (469-821): 2.19e-108: 363: 37.57
+	Hs
		196430 DLG4_HUMAN (1002-1238): 1.07e-27: 123: 17.51		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		230245 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Mm
		1143412 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		SI1L1_MOUSE (1-1719): 0: 1405: 47.86
+	Hs
		196436 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		297818 AFAD_HUMAN (1-1824): 0: 1279: 100.00		K0754_HUMAN (1321-1712): 5.57e-22: 106: 8.52
+	Hs
		1066194 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		RGPA2_HUMAN (502-852): 1.14e-101: 364: 21.63
+	Ce
		105545 DLG1_CAEEL (1010-1092): 1.62e-13: 78.3: 27.06		H2L055_CAEEL (474-871): 1.68e-129: 427: 34.67
+	Hs
		1102434 DLG3_HUMAN (1009-1467): 4.67e-23: 109: 13.25		RGPA2_HUMAN (502-852): 1.14e-101: 364: 21.63
+	Hs
		1151770 DLG3_HUMAN (1009-1467): 4.67e-23: 109: 13.25		RGPA1_HUMAN (504-833): 7.23e-95: 343: 22.99
+	Hs
		835084 INADL_HUMAN (1003-1089): 2.08e-11: 71.8: 25.81		TSC2_HUMAN (538-860): 1.95e-102: 367: 21.07
+	Dm
		114646 PATJ_DROME (969-1164): 1.83e-29: 129: 28.08		M9PD17_DROME (549-818): 3.41e-76: 283: 21.94
+	Hs
		1066964 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		PCLO_HUMAN (1043-1712): 2.32e-13: 78.1: 8.16
+	Hs
		1068686 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		RHG23_HUMAN (960-1528): 4.6e-39: 162: 13.57