HitPredict

Interactor 1: ELL (P55199)
RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)
Gene: ELL

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 20431927
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008023 - transcription elongation factor complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 559
+	Hs
		788019 ELL_HUMAN (1-621): 0: 833: 100.00		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Hs
		130155 ELL2_HUMAN (2-620): 0: 772: 45.76		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Hs
		130146 ELL2_HUMAN (2-620): 0: 772: 45.76		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Hs
		876638 ELL_HUMAN (1-621): 0: 833: 100.00		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		974520 ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Hs
		788066 ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Hs
		297831 OCLN_HUMAN (358-616): 8.61e-79: 260: 25.57		K0754_HUMAN (81-524): 7.09e-22: 102: 10.62
+	Hs
		965110 OCLN_HUMAN (358-616): 8.61e-79: 260: 25.57		ANK2_HUMAN (152-492): 2.61e-11: 68.9: 15.79
+	Dm
		1365313 ELL_DROME (479-619): 3.66e-34: 141: 33.10		Q9VF92_DROME (5-501): 1.12e-32: 135: 22.04
+	Dm
		2367 ELL_DROME (479-619): 3.66e-34: 141: 33.10		A0A0B4KG69_DROME (5-501): 1.13e-32: 135: 22.04