HitPredict

Interactor 1: NP1L1 (P55209)
Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP)
Gene: NAP1L1

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0042393 - histone binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 127
+	Hs
		876805 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		707565 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		876745 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		876845 NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Hs
		1087365 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		420873 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2B1J_HUMAN (1-127): 4.39e-54: 167: 85.04
+	Hs
		707727 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		1282951 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		1231232 NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Dm
		355262 Q24150_DROME (10-391): 3.64e-120: 354: 44.16		H2B_DROME (37-127): 3.48e-47: 149: 94.51
+	Dm
		355275 Q9W1G7_DROME (10-391): 4.29e-120: 354: 44.16		H2B_DROME (37-127): 3.48e-47: 149: 94.51
+	Sc
		355792 NAP1_YEAST (16-390): 4.36e-102: 310: 30.61		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Ce
		1090450 Q19007_CAEEL (51-371): 1.19e-88: 272: 40.62		H2B2_CAEEL (6-127): 6.77e-50: 156: 77.05
+	Ce
		380429 Q19007_CAEEL (51-371): 1.19e-88: 272: 40.62		H2B1_CAEEL (8-127): 5.05e-50: 156: 78.33
+	Hs
		707676 TSYL5_HUMAN (18-357): 2.73e-64: 212: 15.91		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		707747 TSYL1_HUMAN (71-343): 7.16e-63: 209: 18.32		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		886086 SET_HUMAN (62-343): 2.66e-57: 190: 20.28		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		963873 SET_HUMAN (62-343): 2.66e-57: 190: 20.28		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00