Interactor 1: CASP9 (P55211)
Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10]
Gene: CASP9

Interactor 2: CASP9 (P55211)
Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10]
Gene: CASP9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 28716524, 31980649, 15941357
Identification Methods affinity chromatography technology, molecular sieving, cosedimentation in solution, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD, Peptidase_C14~Peptidase_C14
Common GO terms GO:0001666 - response to hypoxia
GO:0001822 - kidney development
GO:0002931 - response to ischemia
GO:0004197 - cysteine-type endopeptidase activity
GO:0005634 - nucleus
and 33 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 416
Hs

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Last updated: 15 Jul 2024