Interactor 1: KC1A (P48729)
Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
Gene: CSNK1A1

Interactor 2: CRBN (Q96SW2)
Protein cereblon
Gene: CRBN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.90 0.913

The method score is based on:

Property Details
Experiments 26131937, 26990986, 26909574, 34489457, 35780831, 37365982
Identification Methods affinity chromatography technology, enzymatic study, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Yippee-Mis18
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025