HitPredict

Interactor 1: CASP6 (P55212)
Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)]
Gene: CASP6

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	32122970
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 1072
+	Hs
		1059341 CASP8_HUMAN (5-289): 3.37e-98: 298: 30.20		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		667483 CASP1_HUMAN (11-291): 1.32e-98: 296: 23.89		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		181632 CFLAR_HUMAN (16-279): 5.47e-71: 228: 22.38		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		876965 CASP7_HUMAN (33-288): 3.89e-113: 330: 38.28		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		788233 CASP3_HUMAN (37-289): 1.09e-110: 323: 41.90		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		683151 CASPE_HUMAN (33-288): 3.86e-71: 221: 27.31		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44