Interactor 1: CASP6 (P55212)
Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)]
Gene: CASP6

Interactor 2: IRAK3 (Q9Y616)
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)
Gene: IRAK3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 21098228
Identification Methods protease assay, anti tag coimmunoprecipitation
Interaction Type protein cleavage, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 293
Hs

1 596
+ Mm

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Last updated: 15 Jul 2024