HitPredict

Interactor 1: RAB8A (P55258)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: SYTL4 (Q9R0Q1)
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Gene: SYTL4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11773082
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0005768 - endosome GO:0005886 - plasma membrane GO:0031267 - small GTPase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 207 Mm			1 673
+	Hs
		894790 RAB8A_HUMAN (1-207): 3.71e-89: 262: 97.10		SYTL4_HUMAN (1-673): 0: 551: 90.34
+	Hs
		1273004 RAB8B_HUMAN (1-207): 8.82e-89: 261: 83.58		SYTL4_HUMAN (1-673): 0: 551: 90.34
+	Hs
		914274 RB11A_HUMAN (4-204): 2.83e-84: 250: 41.55		SYTL4_HUMAN (1-673): 0: 551: 90.34
+	Hs
		914240 RB11A_HUMAN (4-204): 2.83e-84: 250: 41.55		SYTL5_HUMAN (2-671): 6.13e-153: 461: 39.51
+	Hs
		895496 RAB10_HUMAN (3-181): 5.3e-93: 271: 75.98		SYTL3_HUMAN (1-662): 3.73e-122: 378: 29.19
+	Hs
		129082 RAB1A_HUMAN (1-204): 8.1e-90: 264: 53.43		SYT5_HUMAN (354-650): 3.5e-100: 313: 30.20
+	Hs
		1134943 RAB1B_HUMAN (1-204): 5.3e-89: 261: 51.96		SYT6_HUMAN (228-662): 2.65e-87: 284: 21.60
+	Hs
		894765 RAB8A_HUMAN (1-207): 3.71e-89: 262: 97.10		SYTL1_HUMAN (4-486): 2.57e-39: 154: 13.50
+	Mm
		812770 RAB8A_MOUSE (1-207): 9.99e-90: 263: 100.00		RP3A_MOUSE (523-673): 1.6e-27: 120: 22.29
+	Hs
		894828 RAB8A_HUMAN (1-207): 3.71e-89: 262: 97.10		RP3A_HUMAN (523-673): 4.16e-27: 118: 22.89
+	Hs
		1273014 RAB8B_HUMAN (1-207): 8.82e-89: 261: 83.58		RP3A_HUMAN (523-673): 4.16e-27: 118: 22.89
+	Mm
		895586 RAB10_MOUSE (3-181): 5.3e-93: 271: 75.98		RIMS1_MOUSE (128-639): 1.22e-15: 83.4: 14.92