HitPredict

Interactor 1: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1226 Hs			1 2414
+	Hs
		877273 DSRAD_HUMAN (1-1226): 0: 1785: 100.00		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		998999 STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		998624 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		322528 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		1020004 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		1056906 DGCR8_HUMAN (474-762): 2.83e-47: 184: 17.94		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		269734 PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		322631 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		322927 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86
+	Hs
		323384 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		PCLO_HUMAN (533-1087): 8.45e-12: 73.6: 11.83
+	Hs
		944757 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86
+	Hs
		944780 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		944849 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		PB1_HUMAN (1081-1145): 9.68e-11: 69.8: 36.92