HitPredict

Interactor 1: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1226 Hs			1 1912
+	Hs
		877254 DSRAD_HUMAN (1-1226): 0: 1785: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		877324 DSRAD_HUMAN (1-1226): 0: 1785: 100.00		CHD5_HUMAN (86-1909): 0: 1584: 71.18
+	Hs
		1059810 STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1019746 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		322641 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		944785 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1018651 STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018444 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		322538 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		944759 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		944870 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		CHD5_HUMAN (86-1909): 0: 1584: 71.18
+	Hs
		229267 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		322219 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		SMCA1_HUMAN (617-1597): 0: 779: 27.44
+	Hs
		1019960 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		229361 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		658648 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		SMCA1_HUMAN (617-1597): 0: 779: 27.44
+	Hs
		944952 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		CHD8_HUMAN (489-1678): 0: 752: 28.31