HitPredict

Interactor 1: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 32433965
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006397 - mRNA processing and 1 others more... GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1226 Hs			1 551
+	Mm
		1156803 ILF3_MOUSE (504-660): 1.56e-25: 116: 23.30		CPSF6_MOUSE (1-520): 4.58e-92: 294: 99.62
+	Hs
		322696 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		944804 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		585462 E2AK2_HUMAN (505-857): 1.48e-55: 205: 18.45		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		322879 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		322358 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		322569 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		846922 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		302233 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		SC31A_HUMAN (127-488): 4.72e-28: 121: 14.25
+	Hs
		516715 STAU2_HUMAN (470-829): 3.1e-28: 123: 17.54		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		322122 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		944766 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		323384 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		PCLO_HUMAN (131-447): 2.08e-14: 78.8: 12.23
+	Hs
		944922 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59