HitPredict

Interactor 1: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045087 - innate immune response
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1226 Hs			1 482
+	Hs
		877262 DSRAD_HUMAN (1-1226): 0: 1785: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		877334 DSRAD_HUMAN (1-1226): 0: 1785: 100.00		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		585586 E2AK2_HUMAN (505-857): 1.48e-55: 205: 18.45		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		585461 E2AK2_HUMAN (505-857): 1.48e-55: 205: 18.45		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1019999 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Mm
		956352 ILF3_MOUSE (504-660): 1.56e-25: 116: 23.30		G3BP2_MOUSE (1-482): 3.86e-108: 331: 98.34
+	Hs
		323305 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		269719 PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030508 STAU2_HUMAN (470-829): 3.1e-28: 123: 17.54		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		322568 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		322673 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		322611 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Hs
		1272082 STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1272115 STAU2_HUMAN (470-829): 3.1e-28: 123: 17.54		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1019860 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		322953 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		311331 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		CELF2_HUMAN (309-419): 2e-14: 77.2: 18.10