HitPredict

Interactor 1: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27729454, 36252997
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1226 Hs			1 605
+	Hs
		877384 DSRAD_HUMAN (1-1226): 0: 1785: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Mm
		1112923 DSRAD_MOUSE (10-1226): 0: 1545: 76.21		FBW1A_MOUSE (1-605): 0: 547: 98.68
+	Hs
		877337 DSRAD_HUMAN (1-1226): 0: 1785: 100.00		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		269942 PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1020008 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1019991 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		585518 E2AK2_HUMAN (505-857): 1.48e-55: 205: 18.45		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		269826 PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		269908 PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		269670 PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		323214 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		209370 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		903179 ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		322417 STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		944964 RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21