HitPredict

Interactor 1: FOXA1 (P55317)
Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A)
Gene: FOXA1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30572598
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 472 Hs			1 1214
+	Hs
		1021134 FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Ce
		107359 PHA4_CAEEL (4-443): 3.33e-65: 220: 30.32		G5EF87_CAEEL (325-1041): 1.19e-88: 306: 34.96
+	Ce
		110901 PHA4_CAEEL (4-443): 3.33e-65: 220: 30.32		H8ESF3_CAEEL (325-1041): 1.22e-87: 303: 34.96
+	Ce
		110890 FOXO_CAEEL (114-454): 2e-44: 165: 16.67		H8ESF3_CAEEL (325-1041): 1.22e-87: 303: 34.96
+	Hs
		232068 FOXG1_HUMAN (17-470): 1.3e-61: 210: 22.32		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		160205 FX4L1_HUMAN (119-408): 2.33e-50: 178: 31.65		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		877807 FOXA1_HUMAN (1-472): 5.65e-93: 291: 100.00		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Hs
		232132 FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		159980 FOXI1_HUMAN (113-372): 1.78e-46: 167: 28.93		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		261469 FOXK1_HUMAN (107-373): 2.04e-54: 195: 27.24		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		1021390 FOXL1_HUMAN (143-337): 1.76e-55: 190: 42.86		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261490 FOXL1_HUMAN (143-337): 1.76e-55: 190: 42.86		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		261489 FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		1021272 FOXI1_HUMAN (113-372): 1.78e-46: 167: 28.93		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		964295 FOXK2_HUMAN (67-472): 2.52e-43: 163: 20.69		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261471 FOXK2_HUMAN (67-472): 2.52e-43: 163: 20.69		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		1318670 FOXQ1_HUMAN (69-459): 1.06e-43: 160: 24.75		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		1021323 FOXL1_HUMAN (143-337): 1.76e-55: 190: 42.86		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Hs
		1021235 FOXI1_HUMAN (113-372): 1.78e-46: 167: 28.93		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Mm
		70946 FOXO3_MOUSE (46-459): 1.36e-44: 167: 18.72		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78